The TAMPting project’s two common goals:
- understanding how tail-anchored proteins are incorporated into a variety of target membranes;
- using tail-anchored proteins to improve liposome based drug delivery and create artificial membranes.
The overriding ethos of our consortium is to develop a robust platform for the application and exploitation of tail-anchored membrane proteins that operates within a framework where we develop and enhance our knowledge and understanding of their cellular biogenesis.
For a recent review of tail-anchored proteins see: Johnson, N., Powis, K. and High, S. (2013). Biochimica et Biophysica Acta. BBA - Molecular Cell Research 1833: 2403–2409.
The fellows recruited to the TAMPting network are working on the below projects, the ESRs being 36 months and the ERs 24 months in length.